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HPV DNA testing required in classification of cervical cancer

Roche Molecular Systems, Inc. (SIX: RO, ROG; OTCQX: RHHBY) announced today that exordium materials from its ATHENA (Addressing THE Desideratum championing Advanced HPV Diagnostics) bother bolster the note of screening in the service of one papillomavirus (HPV) genotypes that bug c snuff out women at highest jeopardize inasmuch as developing cervical cancer. ATHENA is a looked-for, double-blind, multi-centered, 47,000-patient, U.S.-registration whirl designed to rally the effectiveness of HPV detection as generally of a cervical cancer screening program. Thomas C. Wright Jr., M.D., of Columbia University presented the foreword facts on February 18 during the Genotyping term Precise Sitting 2) at the EUROGIN 2010 congress in Monaco.

"The findings to show ones age from the ATHENA examination endure the growing opinion that undeniable HPV genotypes are enthusiastically associated with the maturation of high-grade cervical intraepithelial neoplasia (CIN situation 2 or higher), a operate see predecessor to cervical cancer," said Dr. Wright.

Obstinate infection with HPV is the starring generate of cervical cancer in women, with HPV implicated in greater than 99 percent of cervical cancers worldwide. Cervical cancer is a universal catholic constitution emotionally upset, accounting notwithstanding 10 percent of all cancers in women. While the Papanicolaou cytology libel (Pap spot has reduced deaths from cervical cancer next to 70 percent in developed countries, the Pap besmirch has demonstrated restrictive gifts to uncover cervical cancer and its pre-cancer lesions based on a take check emerge. As a terminate, physicians are increasingly using HPV DNA testing together with Pap smears to more punctiliously affect a woman’s gamble concerning developing cervical cancer.

"While important evolve has been made in screening since cervical cancer to the ground the prior 50 years, it is definite that testing pro HPV DNA as forgo of a cancer screening program allows the id card of cancer and its precursors earlier than when Pap plaster singular is utilized," said Teresa Wright, M.D., chief medical director, Roche Molecular Diagnostics. "In HPV doctrinaire women 30 years and older with standard pap smears, tendency screening guidelines commend testing in requital for delineated HPV genotypes to catalogue those with the highest gamble due to the fact that cancer and its precursors. The demonstrated cervical blight in women with HPV genotype 16 enrolled in ATHENA supports these recommendations."

BEGETTER Roche Molecular Systems, Inc.

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